Which condition is a common cause of acute renal failure due to obstruction of urinary flow?

Which condition is a common cause of acute renal failure due to obstruction of urinary flow?

• A. Hypovolemia.
• B. Nephrotoxins.
• C. Obstructive uropathy.
• D. Hyperkalemia.

Answer: (C)

Postrenal acute kidney injury occurs when urine flow is blocked anywhere along the urinary tract. Obstructive uropathy describes that blockage, which raises pressure in the kidneys, backs up urine, and reduces glomerular filtration rate. If the obstruction is relieved, kidney function can recover, especially with early relief; prolonged obstruction can cause lasting damage. This makes obstructive uropathy the best explanation for acute renal failure caused by urinary flow obstruction. Hypovolemia causes AKI by reducing renal perfusion (prerenal), nephrotoxins damage the tubules (intrarenal), and hyperkalemia is a consequence or complication of AKI rather than a primary cause of obstruction.

Postrenal acute kidney injury occurs when urine flow is blocked anywhere along the urinary tract. Obstructive uropathy describes that blockage, which raises pressure in the kidneys, backs up urine, and reduces glomerular filtration rate. If the obstruction is relieved, kidney function can recover, especially with early relief; prolonged obstruction can cause lasting damage. This makes obstructive uropathy the best explanation for acute renal failure caused by urinary flow obstruction.

Hypovolemia causes AKI by reducing renal perfusion (prerenal), nephrotoxins damage the tubules (intrarenal), and hyperkalemia is a consequence or complication of AKI rather than a primary cause of obstruction.